5 Comments
User's avatar
Jacob's avatar

I’d bet that we get in vivo targeted LNP delivery to hematopoietic stem cells soon, proof of concept in humans in <5 yrs approval in <10. That’s another whole chunk of diseases you can do personalized edits for!

Eryney Marrogi's avatar

No arguments from me there. Though I took the question to be more about when personalized enhancement type editing will become available, which I think is some ways out.

In any case you’re the LNP expert so you’d know better than me — thanks for reading!

Jacob's avatar

Okay fair but just wait til the Tour de France gets won by a guy who edited his HSCs to produce more Epo

Eryney Marrogi's avatar

You’re not supposed to share that kind alpha for free.

Jacob's avatar

Jokes on anyone who listens to me since oops Epo is apparently mostly secreted from the kidney not made within hscs